Moiz Mumtaz
Instructor
Adjunct Professor
Adjunct or Visiting, Environmental Health
Dr. Mumtaz’s current research interests include the development of toxicity and risk assessment methods for environmental chemicals/pollutants. Service activities have included numerous expert panels for national and international government and NGOs. He is the principal representative of the Agency for Toxic Substances and Disease Registry (ATSDR/CDC) on the Department of Health and Human Services (DHHS) Interagency Coordinating committee on the validation of alternative methods (ICCVAM). He was a member of the Toxic Substances Control Act subcommittee of Society of Toxicology (SOT), SOT Government Liaison Group, and Oregon State University Superfund Center External Advisory Committee. He is a member of SOT and the past - president of its Mixtures Specialty Section. In 2013, he was elected a Fellow of the Academy of Toxicological Sciences (FATS) and won the SOT Lehman award for major contributions to risk assessment and the regulation of chemical agents. During the past three decades, Dr. Mumtaz has actively published his research findings in several peer-reviewed journals. His research interest cover a wide range of research areas pertinent to medicine and human health including dopamine metabolism/mental health, comparative toxicology, analysis of chemicals, use of computational tools in health risk assessment of chemical mixtures and public health.
Contact Information
ATSDR/CDC 1600 Clifton Road, S102-2
Atlanta , GA 30033
Phone: (770) 488-3349
Email: mgm4@cdc.gov
Areas of Interest
- Chemical Exposure
- Environmental Health
- Risk Assessment
- Toxicology
Affiliations & Activities
Society of Toxicology
Publications
- Mumtaz, M.M., Buser, M.C., and Pohl, H.R. (2021). , 2021, Per- and polyfluoroalkyl mixtures toxicity assessment “Proof-of-Concept” illustration for the hazard index approach., Journal of Toxicology and Environmental Health, Part A, ,
- Ruiz, P., Emond., C., McLanahan, E., Joshi-Barr, S., and M. Mumtaz, M.M., 2020, Exploring Mechanistic Toxicity of Mixtures Using PBPK Modeling and Computational Systems Biology, Toxicological Sciences, 174, 38-50
- Patlewicz, G, Lizzarraga, L.E., Ruac, D., Allen, D.G., Daniel, A.B., Fitzpatrick, S.C., Garcia-Reyerof, N., Gordon, J., Hakkinen, P., Howard, A.S., Karamus, A., Matheson, J., Mumtaz, M., Richarz, AN., Ruiz, P., Scaraano, L., Yamada, T., and Kleinstreur, N. , 2019, Exploring current read-across applications and needs among selected U.S. Federal Agencies, Reg. Tox. Pharm. , 106, 197-209
- Myatt, G.J., Mumtaz, M., Allen, D., Ruiz, P. et al , 2018, In Silico Toxicology Protocols, Reg. Tox. Pharmacol. , 96, 1-17
- Faroon, O., Keith, S., Mumtaz, M.M., and Ruiz, P., 2017, Minimal Risk Level Derivation of Cadmium: Acute and Intermediate duration, Jour. Exptal. Clin. Tox. , 1, 1-17
- Emond, C., Ruiz, P., and Mumtaz, M., 2017, Physiologically based pharmacokinetic toolkit to evaluate environmental exposures: Applications of the dioxin model to study real life exposures. , Tox. Appl.. Pharamacol. , 315, 70-79
- Shim, Y.K., Lewin, M. D., Ruiz, P., Eichner, J. E. and Mumtaz, M.M. , 2017, Prevalence and associated demographic characteristics of exposure to multiple metals and their species in human populations: The United States NHANES, 2007–2012, Journ. Toxicol. Environ. Health. Part A, 80, 502-512
- Ruiz, P., Perlina, A., Mumtaz, M.M., and Fowler, B. A. , 2016, A Systems Biology Approach Reveals Converging Molecular Mechanisms that Link Different POPs to Common Metabolic Diseases, Eniron. Health Perspectives, 124, 1034-1041
- Ruiz, P., Aylward, L.L., and M. Mumtaz, 2014, Application of pharmacokinetic modelling for 2,3,7,8-tetrachlorodibenzo-p-dioxin exposure assessment, SAR & QSAR in Environmental Research, 25, 873-890
- Moffett, D., B., Mumtaz, M., Sullivan, D.W., and B. Fowler, 2014, General Considerations of Dose-Effect and Dose-Response Relationships , In: Nordberg, G., Fowler, B., and Nordberg, M. (Ed.): Handbook on the Toxicology of Metals, Academic Press, , 197-212
- Nordberg, G., Gerhardsson, L., Mumtaz, M., Ruiz, P., and B. Fowler, 2014, Interactions and Mixtures in Metal Toxicology, In: Nordberg, G., Fowler, B., and Nordberg, M. (Ed.): Handbook on the Toxicology of Metals, Academic Press, ,
- Ruiz, P., Myshkin, E., Quigley, P., Faroon, O., Wheeler, J., Mumtaz, M., and R. Brennan., 2013, Assessment of hydroxylated metabolites of polychlorinated biphenyls as potential xenoestrogens: A QSAR comparative analysis, SAR & QSAR in Environmental Research, 24, 659-82
- Mumtaz, M., Fisher, J., Blount, B., and P. Ruiz, 2012, Application of Physiologically Based Pharmacokinetic Models in Chemical Risk Assessment, Jour. of Toxicol., doi:10.1155/2012/904603,
- Mumtaz, M.M. and H. R. Pohl, 2012, Interspecies Uncertainty in Molecular Responses and Toxicity of Mixtures, A. Luch (ed.), Molecular, Clinical and Environmental Toxicology, Experientia Supplementum 101, DOI 10.1007/978-3-7643-8340-4_12, Springer Basel AG 2012, ,
- Pohl, H.R., Ruiz, P., Scinicariello, F., and M. Mumtaz, 2012, Joint toxicity of alkoxyethanol mixtures: Contribution of in silico applications, Regul Toxicol Pharmacol, 64, 134-142
- Ruiz., P., Begluitti, G., Tincher, T., Wheeler, J., and M. M. Mumtaz, 2012, Prediction of Acute Mammalian Toxicity Using QSAR Methods: A Case Study of Sulfur Mustard and Its Breakdown Products, Molecules, ,
- Mumtaz, M., Ray, M., Crowell, S., Keys, D., Fisher, J. and P. Ruiz, 2012, Translational Research to Develop a Human PBPK Models Toolkit – Volatile Organic Compounds (VOC), Jour. Toxicol. Environ. Health, 75, 6-24
- Editor: M. M. Mumtaz , 2010, Principles and Practice of Mixtures Toxicology, Wiley-VCH, Federal Republic of Germany, ,
- Dennison, J. E., Bigelow, P. L., Mumtaz, M. M., Andersen, M. E., Dobrev, I. D., and Yang, R. S. H. , 2005, Evaluation of Potential Toxicity from Co-Exposures to Three CNS Depressants (Toluene, Ethylbenzene, and Xylene) Under Resting and Working Conditions Using PBPK Modeling, Jour. Occup. Environ. Hygiene , 2, 127-135
- Mumtaz, M. M., De Rosa, C.T., Cibulas, W. and Falk, H., 2004, Seeking Solutions to Chemical Mixtures Challenges in Public Health, Environ. Toxicol. Pharmacol., 18, 55-63
- Basak, S. C., Denise, M, Mumtaz, M. M., and Balasubramanian, K., 2003, Use of topological indices in predicting aryl hydrocarbon receptor binding potency of dibenzofurans: A hierarchical QSAR approach, Ind. Jour. of Chem. , 42A, 1385-1391
- Mumtaz, M. M., Tully, D. B., El-Masri, H. A. and De Rosa, C. T., 2002, Gene Induction Studies and Toxicity of Chemical Mixtures , Environ. Health. Perspect. , 110(Suppl.6), 947-956
- Khan, M. A., Lichtensteiger, C. A., Faroon, O., Mumtaz, M. M., Schaeffer, D. J. and Hansen, L. G., 2002, The Hypothalamo-Pituitary-Thyroid (HPT) Axis: A Target of Nonpersistent ortho-Substituted PCB Congeners, Toxicol Sci., 65, 52-61